ABMIUM target intelligence

ADAM15

ADAM metallopeptidase domain 15

ADAM metallopeptidase domain 15 (ADAM15), also known as MDC15 or metargidin, is a membrane-associated disintegrin metalloprotease. This ABMIUM target guide links the verified human target identity to catalogue-backed research products and authoritative NCBI/UniProt evidence.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene8751 UniProtQ13444

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Disintegrin and metalloproteinase domain-containing protein 15ADA15MDC15Metargidin

Biological function

ADAM metallopeptidase domain 15 (ADAM15/MDC15) is a membrane-associated disintegrin metalloprotease. Reviewed UniProt describes gelatinolytic and collagenolytic activity together with roles in cell adhesion and migration, E-cadherin cleavage, wound-healing processes and neovascularization-related biology.

Research context

ADAM15 is studied in extracellular proteolysis, cell adhesion and migration, tissue remodelling, wound healing and pathological neovascularization. Reagent selection should still be based on species, sample type, assay format, application and product-level validation.