ABMIUM target intelligence
actinin alpha 3
Actinin alpha 3 (ACTN3), encoding alpha-actinin-3, is a skeletal-muscle actin-binding protein concentrated in fast type 2 fibres. This record connects NCBI Gene 89, reviewed UniProtKB Q08043 and related ABMIUM catalogue products.
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Names used across publications, databases and supplier catalogues.
Alpha-actinin-3, encoded by ACTN3 (actinin alpha 3), is an F-actin cross-linking and bundling protein that contributes to the sarcomeric Z line. It is primarily associated with skeletal muscle, with reviewed UniProt reporting protein expression restricted to fast type 2 skeletal-muscle fibres.
ACTN3 research spans skeletal-muscle architecture, sarcomeric Z-line organisation, actin cross-linking, fibre-type biology and genotype-to-phenotype studies. ABMIUM catalogue products associated with ACTN3 can support target-focused studies; verify species, application, sample type and product-level validation before use.